Objective:To study the clinical and protective effect of combined therapy of mild hypothermia and dormancy in the treatment of severe traumatic brain injury. Methods:62 patients with severe traumatic brain injury (GCS≤8) were randomly divided into mild hypothermia and dormancy therapy group(30 cases) and the control group( 32 cases).The combined therapy of mild hypothermia and dormancy was applied with in 24 hours after admission, the anal temperature at 33-35℃and treatment course of 3 -7 days. According to Glasgow Outcome Scale( GOS) and complication, the prognosis of the patients was evaluated. Results:In comparison with control group, during dormancy treatment and mild hypothermia, mortality was reduced and good recovery rate was obtained,Yet the complications were not increased significantly. Conclusions:The combined therapy of mild hypothermia and dormancy are safe and efective for the prevention of brain injuries in patients with severe cerebral contusion and laceration,free from severe complication.
Severe traumatic brain injuryDormancy treatmentMild hypothermiaComplicationsPrognosi
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