Objective:To investigate the early onset of coronary heart disease in patients with coronary artery disease characteristics and risk factors. Methods:148 cases of coronary heart disease by coronary angiography were divided into groups and premature coronary artery disease coronary heart disease group, the relevant information on the two groups of patients were retrospectively analyzed. Results: Premature coronary heart disease group compared with coronary heart disease have differences. Conclusion: smoking, family history of coronary heart disease, hypercholesterolemia premature coronary artery disease are major risk factors for coronary artery disease mainly characterized by single-vessel disease.