Objective:To explore the effect of personalized nursing in ophthalmology operation patients. Methods:260 cases of ophthalmology operation patients were randomly divided into two groups, 130 cases in the control group were received general nursing, 130 cases in the experimental group were given personalized nursing on the basic of general nursing, and the effects of two groups were compared. Results:After receiving individualized nursing, the anxiety relieve were significantly better than that in the control group(P﹤0.05); The patient's satisfaction in the experimental group were significantly higher than that in the control group(P﹤0.05). Conclusion:Personalized nursing can reduce the anxiety level of ophthalmology perioperative patients, improve patient's satisfaction, it is wel worth clinical application.