objective: patients with bronchial pneumonia by using different atomization inhalation therapy, to observe and analyze the clinical effect of treatment. Methods:our hospital at the records of 180 patients with infantile bronchial pneumonia, the grouping according to random number table method for experimental group and control group, each of 90 cases. Control group: the patients treated by ultrasonic atomizing inhalation method. Treatment group: by using oxygen atomization inhalation therapy on the patients. Results:two groups of patients in the improvement of the clinical signs and symptoms and life time, and so on and so forth, experimental group was bet er than control group, (P<0.05). Control patients and 1 h after suction in the atomization inhalation, the SPO2 compared with the experimental group, the decrease of its apparent (P<0.05). In addition, the experimental group patients of crying and treatment interruption occurring probability significantly lower than the control group, (P<0.05). Conclusion: clinical y, patients with infantile bronchitis by using oxygen atomization inhalation treatment, effectively relieve the symptoms of patients with shorten the treatment time, and less adverse reaction, and is worth popularizing in clinical application.