OBJECTIVE:To analyse o of the reason postoperative pulmonary infection of brain tumor patients for taking effective preventive measures . METHODS:A retrospective analysis of our hospital from June 2012 to December 2012 neurosurgery hospitalized after surgery, 43 cases of brain tumors occur in with severe pulmonary infection clinical data were analyzed factors related to lung infections and summarize the method of preventive care. RESULTS:Brain tumor surgery in patients with severe pulmonary infection and smoking history, preoperative pulmonary infection is not control ed, preoperative combined old chronic bronchitis, endotracheal intubation anesthesia for a long time, postoperative vomiting, poor expectoration and aspiration, immunity low and cross-infection, invasive operation and pol ution. CONCLUSIONS:By reason of the clinical preventive care to take targeted measures to reduce brain tumor surgery in patients with severe pulmonary infection incidence.