objective: To investigate the effect of transparent dressing on prevention of phlebitis that caused by Oxal ipatin.Methods:There were 100 cases were randomly divided into two groups in the experiment:①experimental group(EG:52cases):Fixed remaining needle with Transparent dressing ②Control group(CON:48cases):Fixed remaining needle with 3M Transparent Application, Compareing the incidence of phlebitis similar between the two groups.Results: The phlebitis incidence was 5.76% in experimental group,while in Control group it was 45.8%, with statistical y significant difference beween two groups(χ2=21.368, P=0.000<0.05).Conclusions:transparent dressing can effectively reduce the incidence of phlebitis caused by chemotherapy with oxaliplatin.