objective:to analysis the clinical features of severe pulmonary tuberculosis patients with diabetes mel itus and research, and to explore the diagnosis and treatment of related methods. Methods:in our hospital by the treated 138 cases of severe pulmonary tuberculosis patients with diabetes mel itus, grouped according to blood glucose control in patients with conditions, were divided into experimental group (84 cases) and control group (54 cases). Control group:the patients with poor control of blood sugar; Treatment group: good blood glucose control. Results: treatment group effectiveness is superior to control group, and group in patients with pulmonary tuberculosis recurrence rates and complications related to significantly lower than the control group, significant difference, statistical y significant (P<0.05). Conclusion:clinical y, due to the severe pulmonary tuberculosis patient's condition is very critical and complicated with diabetes mel itus, patients have very strong infectivity, in addition, for patients, blood glucose control is good or bad and the treatment of patients with pulmonary tuberculosis disease has a lot to do.