目的：探讨沧州地区高血压人群血压与脂质代谢及血尿酸水平的关系及临床意义。方法：采用随机整群抽样方法抽取沧州某几个乡镇村民2875例，比较高血压组与非高血压组血脂及血尿酸水平变化。结果：(1)甘油三酯(Triglyceride TG)、低密度脂蛋白(Low density lipoprotein LDL-C)、总胆固醇(Total cholesterol TC)均明显高于非高血压组，而高密度脂蛋白(High density lipoprotein HDL-C)明显低于非高血压组。(2)血脂、血尿酸(Uric acid UA)异常的高血压患病率明显高于血脂、血尿酸正常者，且相关性分析显示高血压分级与UA、TC、TG呈正相关。结论：沧州地区人群血尿酸和血脂异常是高血压病的危险因素，血脂或血尿酸异常与高血压常并存于同一个体中，临床治疗中在降压的同时应积极干预危险因素。
Objective:To analyze the correlation and clinical significance between blood lipid metabolism, serum uric levels and hypertension in Cangzhou areas. Methods:Col ect 2,875 cases of the rural residents by cluster random sampling method from some counties in Cangzhou areas and compare the levels of blood lipid and uric acid in hypertensive and non-hypertensive group. Results:(1) serum uric levels in hypertension group was significantly higher comparing with non-hypertensive group (P<0.05); Similarly , triglyceride (TG), low density lipoprotein(LDL-C) and total cholesterol (TC) were significantly higher than non-hypertensive group, while high density lipoprotein (HDL-C) was Obviously lower compared with non-hypertensive group. (2) Persons with abnormal blood lipids or uric acid (UA) was more likely suffering from hypertension than the normal of it. And the correlation analysis showed that hypertension grading and UA, TG, TC were positively correlated. Conclusion:Uric acid or dyslipidemia is a risk factor of hypertension for people in Cangzhou area and abnormal blood lipids or UA and hypertension coexist regularly in the same individual. So while lowering blood pressure in the clinical treatment, we should actively intervene risk factors.
NETL
NSTL
万方数据
