Objective:To observe the effect of dexmedetomidine on early postoperative comfort in patients with urinary catheterization. Methods:One hundred male patients underwent spinal surgery, ASA I~II, were equal y divided into observation group and control group. The patients in observation group were intravenously infused Dex1ug/kg within 10min via a pump, and continuous infusion of 0.2~0.4 ug.kg-1.h-1 and were stopped at 30min before the end of surgery. The control group received saline. After the induction of general anesthesia, al patients underwent urinary catheterization. Steward score was referenced and extubation was performed when steward score was more than 4. Comfort rating of surgical incision, pain scores of urinary tract, mean arterial pressure (MAP), heart rate (HR ) and SpO2 values were recorded at 5min (T1), 15min (T2) and 30min after extubation. Results:There was no difference in satisfaction rate of urinary tract pain at T1, however, satisfaction rate in the observation group was higher at T2, T3 ( p<0.05 ). The BCS ratings of patients in both groups were high and there were no difference in satisfaction at each time point between the two groups (p>0.05). There were no significant changes in MAP at different points within the observation group;HR at T3 slowed down than at T1 (p<0.01). The blood pressure at T3 than T1 was significantly higher within control group (p<0.01);HR at T2 or T3 was significantly increased than T1 (p<0.01). There were significant changes in MAP and HR between two groups at T2 and T3 (p<0.01). SpO2 at different points was within the normal range. Conclusion:Dex can effectively reduce urinary tract pain caused by urinary catheterization in male patients after general anesthesia, reduce the rate of agitation during anesthesia recovery, and increase patients’ comfortable degree.
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