Objective:to analyze the clinical manifestation of disease in patients with different types of stem, etiology and treatment. Methods:from 2011 February to 2013 February admit ed to our hospital in 236 cases (472 eyes) of clinical data of patients with dry eye and slit lamp examination, corneal fluorescein staining;intimal rupture time check and basal tear secretion test. Results:236 patients with fluid deficiency dry eye 83.89%, MGD4.24%, 11.87%mixed dry eye. More women than men, female 141 cases (59.75%), 95 cases were male (40.25%). Conclusion:the clinical manifestation of patients with dry eye with diversity, according to different causes, different clinical symptom treatment and psychological intervention, combined treatment of traditional Chinese medicine with satisfactory results.