Relationship between different levels of NAFL and HS-CRP
Objective:To investigate and analyse the relationship between different degrees of non-alcoholic faty liver and high-sensitivity C-reactive protein (HS-CRP) in patients with non-alcoholic faty liver disease (NAFLD).Methods:109 patients with NAFLD were selected and divided into three groups ,namely mild,moderate and severe degree of faty liver,according to patients’ ultrasound, CT and biochemical tests results. Serum HS-CRP levels from three groups and the indicators (ALT, AST, TB, GGT, LDL-C, CHOL, HDL-C and TG) of different HS-CRP levels from al patients were compared. Results the average level of HS-CRP was(3.3±2.6)mg/L in the mild group,(5.8±3.7)mg/L in the moderate group and(7.3±3.5)mg/L in the severe one. In the comparison of indicators (ALT, AST, TB, GGT, LDL-C, CHOL, HDL-C and TG) of different HS-CRP levels, the indicators of the HS-CRP level in the range of 3.1-6mg/L has no significant difference with the the standard group with the level in the 0~3mg/L range, while the indicators (ALT, AST, TB, GGT, LDL-C, CHOL and TG)of the two groups with the HS-CRP level in the 6.1~9mg/L and over 9mg/L range were significantly different from the standard group(P<0.05). Conclusions:The varing degrees of the faty liver in patients with NAFLD was closely related to the level of HS-CRP ,thus HS-CRP can be used as an important indicator to evaluatethe development of NAFLD.thus HS-CRP can be used as an important indicator of the assessment of the development of NAFLD.
non-alcoholic faty liver diseasehigh-sensitivity C-reactive protein