To observe the clinical curative effect of Guizhi FulingCapsule and tamoxifen tablets in the treatment of hyperplasia of mammary glands.Methods:60 patients with hyperplasia of mammary gland diseasediagnosed cases, given Guizhi Fuling Capsule and tamoxifen tablets oraly,for 25 days to 1 course of treatment, a total of 2 courses of treatment,observation of symptoms before and after treatment, signs of change and the course of disease, and clinical evaluation. Results: the clinical cure in 31 cases (51.7%); 19 cases (31.7%); 7 cases were effective (11.6%); 3 cases were invalid (5%); the total efficiency of 95%.Conclusion:Guizhi FulingCapsule and tamoxifen tablets in the treatment of breast hyperplasia diseaseclinical curative effect.