The effective observation on Wenxin Granules joint Mexiletine for frequent ventricular arrhythmia
To observe the effect and security of Wenxin Granules joint Mexiletine for frequent ventricular arrhythmia. Methods:Totaly 120 cases of frequent ventricular arrhythmia(VA) were randomized into the observation group and control group ,with 60 in each. The control group were given Mexiletine tablets ,observation group were given Wenxin Granules joint Mexiletine tablets.Both groups were given conventional therapy.The treatment lasted for 4 weeks.Record the heart rate and the number of VA,determinate QT interval dispersion(QTd) before and after treatment in both groups,observe the effect and security.Results:the heart rate of the observation group was obviously slower than control group and QTd significantly lower than control group,with a significant difference between groups (p<0.05).The effective rate in the observation group and control group was 90.0% and 75.0% respectively,with a significant difference between groups (p=0.01, x2=4.51).Conclusion:Wenxin Granules joint Mexiletine have a good effect in the treatment of frequent ventricular arrhythmia,and less adverse reactions,is worthy of popularization and application.
NETL
NSTL
万方数据
