The Clinical Analysis of Non-alcoholic Fatty Liver Disease among Schizophrenia lnpatients
Objectve:To investigate the prevalence of non-alcoholic faty liver in schizophrenic inpatients and its related risk factors.Methods:150 schizophrenia inpatients treated in Shanghai Mental Health Center received body mass index (BMI),blood pressure and ultrasonography of liver.Serum level of several biochemical materials were measured, which including fasting blood glucose,blood fat,liver function and uric acid.Results:The prevalence of non-alcoholic faty liver in schizophrenic inpatients was 34%,the BMI,waist circumference,hip circumference and blood pressure were significantly higher than those without faty liver(P<0.05);in addition to apolipoprotein A (ApoA1),alkaline phosphatase (AKP) than other blood fat,liver function,blood glucose and uric acid were not associated with faty liver were significantly different(P <0.05);Long-term smokers seem to show a positive correlation with the occurrence of faty liver (P <0.05);the comparison is no significant difference between the drug (P> 0.05).Obesity,diabetes, dyslipidemia,smoking is associated with risk of faty liver (withβ of 2.642,2.412,1.406 and -2.237 respectively).Conclusion:Non-alcoholic faty liver occures in many schizophrenia inpatients,obesity,diabetes, dyslipidemia and smoking is a faty liver with factors and a risk factor for cardiovascular disease.Much atention should be paid even in the early course of ilness.
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