Resting heart rate and functional mitral regurgitation in heart failure：effect of intraventricular conduction delay
Objectives: Resting heart rate and Mitral regurgitation(MR) are frequently abnormal in clinical heart failure. The aims of this study were to examine the frequency of functional MR and to investigate the resting heart rate and MR as wel as left ventricular performance in these patients .Subjects and method: 55 normal subjects, 52 patients with heart failure and normal intraventricular conduction and 40 heart failure patients with intraventricular conduction delay underwent Doppler echocardiographic examianation,Results: Compared with normal subjects ,resting heart rate were increased in heart failiue patients with or without intraventricular conduction delay . 3 normal subjects had mild functional MR, 57%(30/52) patients with heart failure and normal conduction had functional MR, 92%(37/40) functional MR were detected in patients with heart failure and intraventricular conduction delay. LV total isovolumic time per minute increased and total filing time per minute were reduced in such patients(p<0.01).Conclusion: In patient with heart failure, resting heart rate were significant increased. MR was common in patients with heart failure with intraventricular conduction delay. Total diastolic and filing time were significant reduced. Left ventricular mechanical efficiency compromised in such patients.
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