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辛伐他汀对高血压患者的临床意义

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目的:探讨辛伐他汀对血脂正常的高血压患者的血压控制情况及心血管事件发生率的影响。方法:180例门诊高血压患者,随机分成常规治疗组(90例)与辛伐他汀组(90例),所有病人均给予钙离子拮抗剂联合血管紧张素转换酶抑制剂(ACEI)的降压常规治疗,辛伐他汀组加服辛伐他汀胶囊20mg/ d。并随访1年,观察两组患者血压控制情况以及心血管事件(心绞痛、心肌梗死、心功能不全)发生率的差异。结果:治疗1年后,辛伐他汀组血压以及心血管事件的发生率均较常规治疗组显著下降(P <0.05)结论:加用辛伐他汀可以更好的控制血压,并减少高血压患者心血管事件的发生率。
To investigate the effect of simvastatin on blood lipid incidence in patients with hypertension and normal blood pressure control and cardiovascular events. Methods:180 cases of patients with hypertension, were randomly divided into routine treatment group (90 cases) and simvastatin group (90 cases), al the patients were treated with calcium antagonist combined with angiotensin converting enzyme inhibitor (ACEI) of antihypertensive treatment, simvastatin group were treated with simvastatin capsules of 20mg/ D. And 1 years of folow-up, two groups were observed in patients with blood pressure control and cardiovascular events (heart function of angina, myocardial infarction, no difference in the incidence of total).Results:after 1 years of treatment, simvastatin group blood pressure and cardiovascular events were compared with routine treatment group decreased significantly (P <0.05)conclusion:blood pressure control with simvastatin can beter, and reduce the incidence of cardiovascular events in patients with hypertension.

simvastatinhypertensioncardiovascular events

董晓明、高丽华

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山东省商河县人民医院 251600

辛伐他汀 高血压 心血管事件

2014

中国保健营养(中旬刊)
全国卫生产业企业管理协会

中国保健营养(中旬刊)

ISSN:1004-7484
年,卷(期):2014.(7)
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