To evaluate the efficacy Carboprost Methylate Suppositorites combined with mifepristone and rivanol on ending Mid-pregnancy
To study the effect of carboprost methylate suppositories combined with mifepristone on ending Mid-pregnancy. Methods:113cases pregnant women who had Mid-pregnancy in hospital from 2012 October to 2013 October were slected and required to ending pregnancy. The 113 patients were randomly divided into observation group and control group. There are 55cases in the observation group and 58cases in the control group. The observation group were given mifepristone 50 mg, one time at morning and night, Medication before and after 2 hours of fasting,even for 3 days,3 days later, according to the degree of cervical softening and uterine contraction, Every 3-6 h posterior vaginal fornix placed Carboprost methylate suppositorites 1 mg, and stay in bed for 30 minutes, The maximum dose does not exceed 4mg. The control group was given amniotic cavity injection of Ethacridine lactate 100 mg to ending pregnancy. To compared the clinical efficacy of two groups.Results:To compare the complete abortion rate of observation group and control group, the observation group was 81.81%, the control group was 63.79%, P<0.05,there was significant difference between two groups; To compare the arbortive time of observation group and control group ,the observation group was 5.82±2.65 h , the control group was 58.24±3.48 h, P<0.05,there was significant difference between two groups; To compare the vaginal bleeding volume of observation group and control group, the observation group was 89.43±6.28 ml, the control group was 168.56±23.32 ml, P<0.05,there was significant difference between two groups . Conclution:Carboprost methylate suppositories combined with mifepristone on ending Mid-pregnancy, to solve the problem of short gestational weeks, less amniotic fluid, puncture difficulties, and cervical conditions are not ripe, To avoid the possibility of uterine cavity operation and intrauterine infection, safe and noninvasive, economic and convenience, easy to operate. It is worthy of clinical promotion.
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