首页|269株铜绿假单胞菌的临床分布及耐药性分析

269株铜绿假单胞菌的临床分布及耐药性分析

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目的:分析铜绿假单胞菌(PA)的临床分布及耐药性,为临床治疗PA感染提供参考依据。方法:采用常规方法分离,用Microscan walkAway一96全自动微生物分析仪进行菌种鉴定,用K-B法进行药敏试验。细菌分离培养按照《全国临床检验操作规程》(第3版)进行,药敏结果按照美国临床实验室标准化研究所(CLSI)标准进行结果判断。采用WH0NET5.4完成数据的统计分析。结果:269株PA主要来源于痰(共201株,占74.7%)其次为尿和分泌物(分别为14株,各占5.2%)。PA对阿米卡星的敏感性最高,其次依次为哌拉西林(他唑巴坦)、美罗培南、头孢吡肟、亚胺培南。结论:PA 主要引起呼吸系统的感染,其次为泌尿系统。PA 对阿米卡星的敏感性最高,其次为哌拉西林(他唑巴坦)、美罗培南等,临床应根据药敏试验结果选择合适的抗菌药物,降低PA的耐药性。
Clinic distribution and Antibiotics Resistance Pattern of 269 Clinical Isolates of Pseudomonas Aeruginosa
To determine the distribution rate and antibiotics resistance pattern in P.aeruginosa among clinical isolates by retrospective analysis and provide reference for the choice of therapy for P.aeruginosa infections. Methods:The strains of P.aeruginosawere isolated from different clinical specimens were characterized was carried out by the by MicroScan WalkAway96 plus Instrument. The antibiotics susceptibility patterns of each isolate were determined by K-B method according to the CLSI guideline. The statistic analysis of drug resistance was performed by WHONET 5.4 software.Results: The majority of the 249 P.aeruginosa were from sputum samples (201/249, 74.7%), the rest were from urine (14/249, 5.2%) and (14/249, 5.2%). The most effective antibiotic is Amikacin, followed by piperacillin (tazobactam), meropenem, cefepime and imipenem. Conclusion: Respiratory tract infections and urinary tract infections were the most common P. aeruginosa sources. The most effective antibiotic is Amikacin, followed by piperacillin (tazobactam), meropenem, cefepime and imipenem.

Pseudomonas aeruginosaappropriate use of drugAntibiotics resistanc

符月春、席云、梁家隐、邹碧姬、陈月燕

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中山大学附属第三医院 检验科 广东 广州 510630

铜绿假单胞菌 合理用药 耐药性

2014

中国保健营养(中旬刊)
全国卫生产业企业管理协会

中国保健营养(中旬刊)

ISSN:1004-7484
年,卷(期):2014.(7)
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