Clinic analysis of sequential noninvasive-invasve mechanical ventilation in treating acute respiratory distress syndrome
Objective To investigate the treatment efficiency of acute respiratory distress syndrome ,with the application of direct invasive ventilation and forced in-vasive ventilation after the failure of no -invasive positive pressure ventilation.Methods The clinical data of ARDS patients with the application of direct IV and NIPPV-IV were retrospectively analyzed from January 2008 to January 2011.Results direct IV group was 90 patients and NIPPV -IV group was 47 patients,the analysis showed that sexual,age,the acute physiology and chronic health evaluation Ⅱ(APACHEⅡ)scores,sequential organ failure assessment(SOFA)scores,simple acute physical(SAPⅡ)scores,lung injury scores,the original of ARDS,sepsis severity were no significant between direct IV group and NIPPV -IV group(p>0.05),after the different mechanical ventilation,the number of organ dysfunction,treatment days in ICU and mortality were significant between direct IV group and NIPPV -IV group(p<0.05).Conclusions ARDS patients should be established artificial airway directly for the application of invasive ventilation ,NIPPV should be used with caution in ARDS patients in order to avoid poor prognosis by its failure .