Objective To observe the induction of general anesthesia in laparoscopic surgery ,the application of dezocine inhibiting effect of endotracheal intubation response and postoperative analgesia analgesic efficacy and patient awake extent.Methods 50 patients with laparoscopic surgery in patients aged 22 to 50 years old,were randomly divided into dezocine group(D group)and fentanyl group(F),n=25.Two groups of patients were treated with inhalation general anesthesia.Induction of anes-thesia:The patient enters the operating room after the intravenous injection of midazolam 0.05mg/kg,D group intravenous dezocine 0.2 -0.3mg/kg,F group,intrave-nous fentanyl 4-6ug/kg,drowsiness after patients intravenous etomidate 0.4mg/kg,vecuronium 0.12mg/kg,achieve intubating conditions after oral endotracheal intuba-tion photopic down.Maintenance of anesthesia:After two computers was intravenous infusion pump infusion of propofol ,remifentanil,according to need intermittent intra-venous injection of vecuronium to maintain muscle relaxation .At the end of surgery followed by intravenous electronic pump .Be reached after extubation testify remove the catheter and record recovery time;remove the catheter nausea,vomiting,respiratory depression,chills and other adverse reactions.OUTCOME MEASURES:Two groups of patients were observed and recorded before induction of anesthesia(T0)intubation(T1)each time period mean arterial pressure(MAP),heart rate(HR)chan-ges in the endotracheal tube to be removed after the patient awake,respectively,in awake instantly(t0),1 hour after awakening(t1)two groups of patients were on a visu-al analogue pain scale(VAS),and Brinell comfort score(BCS)and Bamsay sedation score.Results The patients in endotracheal intubation(T1)are very good suppression of tracheal intubation response,but the F group of patients MAP,HR decline were more obvious compared with the D group was significantly(P<0.05);patients were a-wake time and extubation time was not statistically significant(P>0.05);in the wake immediately(t0),two groups of patients with visual analog pain score(VAS)D was significantly lower than group F(P<0.05),Brinell comfort score(BCS)D group was significantly higher than the F group(P<0.05);in 1 hour after awakening(t1)pa-tients were VAS,BCS score difference was not statistically significant(P>0.05).Conclusion The application of laparoscopic surgery dezocine induction of anesthesia can achieve sufficient depth of anesthesia,the patient's stress response intubation played a good inhibition,and in the conditions to achieve intubation little effect on the circulation of patients,the patient awake extubation time had no significant effect,but after extubation patients showed lethargy,tracheal extubation in patients with post-operative pain scores were lower onset of analgesia pump connected to more reasonable .
dezocineLaparoscopic surgeryInduction of anesthesiaIntubation reactionPostoperative analgesia
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