Objective To study the improvement of micro pump pumping urokinase clinical curative effect for the treatment of lower extremity deep vein thrombosis . Selection methods From October 2012 in September 2013 in our department in the hospital treatment of lower extremity deep vein thrombosis ( DVT) of 120 cases of pa-tients,both by colour to exceed diagnose,modified micro pump were randomly divided into treatment group(A)60 cases,traditional limb static point group 60 cases ( group B) .Results Hospital group A was better than group B;Were followed up for 6-10 months,long curative effect in group A is better than that of group B .Conclu-sion Modified micro pump pumping urokinase treatment of lower extremity deep vein thrombosis can obviously improve the prognosis ,reduce the incidence of PTS,worth clinical promotion.