Objective To investigate clinical effect of spironolactone in treatment of elderly patients with chronic heart failure .Methods 43 patients with chronic heart failure in our hospital from June 2010 to November 2012 were divided into the control group(20),treated by ACEI(angiogenesis-converting enzyme inhibitors) and the observation group(23),treated by spironolactone on the basis of control group.The 6min walk distance and improved heart function change of two groups was an-alyzed.Results After treatment,the 6min walk distance of the observation group(560.2 ±71.9)m was significantly higher than that of the control group(P<0.05).The LVEDD(50.5 ±5.3)mm、LVEF(0.59 ±0.06)of the observation group were better than that of control group(P<0.05).Conclusion The spironolactone in the treat-ment of elderly patients with chronic heart failure have excellent outcomes and can significantly improve heart function in patients .
SpironolactoneElderly patients with chronic heart failureClinical observation
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