Objective To investigate clinical effect of aspirin enteric -coated tablets combined clopidogrel treatment for angina pectoris .Methods Clinical record data of 188 cases of angina patients in our hospital from September 2008 to February 2013 were reviewed.Results After treatment,the total effective rate of the treatment group,(90.43%)was significantly higher than that of the control group(78.72%),with a significant difference(P<0.05).The seizure frequency,seizure interval,24h total time of ischemia and myocardial oxygen consumption index of treatment group were significantly lower than that of the control group (P<0.01).Conclusion Aspirin enteric-coated tablets combined clopidogrel treatment of angina pectoris significant clinical efficacy with clinical value .