首页|经导管肝动脉化疗栓塞联合手术切除治疗肝细胞癌破裂出血25例临床分析

经导管肝动脉化疗栓塞联合手术切除治疗肝细胞癌破裂出血25例临床分析

Clinical Analysis of Transcatheter Arterial Chemoembolization Combiened with Surgical Resection in Treatment of 25 Patients Presented with Ruptured Hepatocellular Carcinoma

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目的:探讨分析经导管肝动脉化疗栓塞( TACE)联合手术切除治疗肝细胞癌破裂出血的临床效果。方法对我院2003年2月---2013年2月收治的80例肝癌破裂出血患者的临床资料进行回顾性分析。其中TACE治疗58例,手术切除22例,TACE 后再手术切除25例。结果80例肝癌劈裂出血患者中,58例患者经TACE治疗后,休克得到及时纠正,生命体征较快稳定,复查CT结果显示肿瘤缩小。其中25例 TACE治疗1个月后,行二期肿瘤切除术,AFP均正常或下降,治疗效果较好。22例一期手术者,3例手术后死亡,13例发生腹腔肿瘤移植转移。结论 TACE可减少肿瘤不可切除者的剖腹探查止血手术、有效治疗肝癌破裂出血、提高肿瘤的切除率。 TACE联合手术切除可显著降低肿瘤的腹腔种植转移率(P<0.05)。
Objective To study and analysis the clinical efficacy of transcatheter arterial chemoembolization( TACE) combined with surgical resection in the treat-ment of ruptured hepatocellular carcinoma(HCC).Methods The clinical date of 80 patients were retrospectively,who presented with ruptured HCC to oua hospital from February 2003 to February 2013.These patients received TACE(n=58),surgical resection(n=22),and sutgical resection after TACE(n=25).Results Shock in 58 patients who receiced TACE was promptlu corrected,and the vital signs were stabilized.On subsequent CT,the tumors shrunk in size.Salvage liver resection was carried out in 25 petients one minth after TACE.After treatment,AFP became normal or decreased,thus the treatment results were good.Aone-stage liver resection was carried out in 22 patients.Three patients died after operation,and peritoneal metastases occurred in thirteen patients.Conculsions TACE efficaciously stopped bleeding from rup-tued HCC,reduced the need for exploration,and improved the rate of resection of HCC.TACE combined with surgical resection significantly lowered the rate of abdominal tumor metastases(P<0.05).

Transarterial chemoemboliaztion(TACM)HepatectomyHepatocellular cancer(HCC)RuptureClinical analysis

李新辉

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河北省邯郸市第一医院普外三科,河北 邯郸 056002

经导管肝动脉化疗栓塞(TACE) 肝切除术 肝细胞癌(HCC) 破裂出血 临床分析

2014

中国保健营养(上旬刊)
全国卫生产业企业管理协会

中国保健营养(上旬刊)

ISSN:1004-7484
年,卷(期):2014.(1)
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