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急性心肌梗死患者的临床治疗研究

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目的:探讨替罗非班对急性心肌梗死患者介入治疗中的临床有效性。方法回顾性分析我院2012年2月---2013年2月收治的80例急性心肌梗死患者,随机分为对照组40例给予皮下注射低分子肝素、口服阿司匹林、氯吡格雷治疗;治疗组40例在对照组基础上给予介入术后1小时内开始应用替罗非班,持续泵入至术后36小时。加用替罗非班,比较两组患者术后出血事件、心功能状态、不良心脏事件、心肌损伤标记物肌酸激酶同工酶( CK-MB)及BNP含量情况进行比较。结果两组患者的不良心脏发生率以及TIMI分级差异有统计学意义(P<0.05);心功能指标:治疗组患者LVEF明显高于对照组(P<0.05),LVEDD和LVESD明显小于对照组(P<0.05),CK-MB和BNP含量明显低于对照组(P<0.05),出血的发生率两组间比较差异无统计学意义(P>0.05)。结论在急性心肌梗死介入治疗中,采用替罗非班能改善急性心肌梗死患者PUI术后梗死相关血管的TIMI血流,减少PCI术后主要不良心脏事件的发生率,因此在临床值得推广使用。
Objective To explore for class had clinical effectiveness of interventional therapy in patients with acute myocardial infarction .Methods Retrospective a-nalysis in February 2012-February 2013 treated 80 cases of patients with acute myocardial infarction ( mi) ,40 cases were randomly divided into control group given sub-cutaneous injection of low molecular heparin and oral aspirin and clopidogrel treatment;Treatment group 40 cases in the control group on the basis of giving within 1 hour after interventional started application for class,had continued pumping to 36 hours after surgery.Used for class,had to compare two groups of patients with postoperative bleeding events,heart function,adverse cardiac events and myocardial injury markers creatine kinase isoenzyme(CK-MB)and BNP levels were compared.Conclusion Interventional therapy in acute myocardial infarction ,can use for class had improve PUI infarction after operation in patients with acute myocardial infarction related blood vessel TIMI flow,reduce the incidence of major adverse cardiac events after PCI,therefore in clinical use to be promoted.

Acute myocardial infarctionInterventional therapyFor class had

姚飞

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新疆乌鲁木齐市第一人民医院内三科,新疆 乌鲁木齐 830011

急性心肌梗死 介入治疗 替罗非班

2014

中国保健营养(上旬刊)
全国卫生产业企业管理协会

中国保健营养(上旬刊)

ISSN:1004-7484
年,卷(期):2014.(1)
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