摘要
目的：探讨血清骨钙蛋白（ OC）水平在儿童营养性佝偻病患儿诊断和骨代谢评价体系中的临床价值。方法选取42例佝偻病患儿（病例组）及40例健康儿童（对照组），每位儿童均采集空腹静脉血2mL，采用ELISA法分别测定其血清骨钙蛋白水平，并对检测结果进行分析。结果42例佝偻病患儿血清骨钙蛋白水平为（13．22±3．78）ng/mL，显著高于健康儿童组（7．25±2．63）ng/mL（t＝9．677，P＜0．001），有统计学意义。结论血清骨钙蛋白水平可作为儿童营养性佝偻病的诊断及骨代谢评价的一项重要敏感指标。
Abstract
Objective To explore the clinical Value in the evaluation system of bone metabolism in children with Rickets .Methods Forty-two with Rickets and forty normal children were selected,Every children was gathered 2 mL venous blood,The concentration of osteocalcin(OC)by enzyme linked immunosorbent assay (ELISA),calculate the contents of OC.Do the further analysis of the results.Results The levels of serum OC in patients group was(13.22 ±3.78)ng/mL,and the levels of serum OC in the control group was(7.25 ±2.63)ng/mL,The difference was significant(P<0.001 t=9.677).Conclusion The serum OC could be an objective indi-cator to evaluate the children’ s bone metabolism and diagnose of children with Rickets.
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