Objective Investigate the video -assisted thoracoscopic lung volume reduction surgery in the treatment of chronic obstructive pulmonary emphysema with preoperative preparation and surgical care.Methods January 2007 to 20l2 December,21 cases in our hospital thoracoscopic lung volume reduction surgery in pa-tients with chronic obstructive pulmonary emphysema,get preoperative preparation,intra-operative medical staff with the implementation of surgery .Results 21 surgeries were successfully completed,without conversion to thoracotomy,intraoperative blood transfusion,postoperative wound infection,mean operative time was 109.1 ±10. 4min;postoperative chest drainage remain indwelling average 6.0 ±1.1d;postoperative hospitalization time of 10.7 ±6.3d.2 patients postoperative complications oc-curred in 2 cases(9.5%),in which the lung persistent air leak >7d,1 cases,pulmonary infection in 1 case,postoperative 1 second forced expiratory volume(FEV1),to-tal lung capacity(TLC),residual volume(RV),arterial oxygen pressure(PaO2),arterial carbon dioxide partial pressure(PaCO2),the difference was statistically signifi-cant(P<0.05)6MWT compared with the preoperative.Follow-up of 18 patients(85.7%),the follow-up period of 6 months to 2 years,review of blood gas analysis, the 6MWT and pulmonary function improved significantly compared with preoperative difference was statistically significant (P<0.05).Conclusion Video-assisted tho-racoscopic implementation of lung volume reduction surgery has little damage,quick recovery,high-quality care with the patients can get the best results of operations, improve the success rate of surgery,postoperative rehabilitation is essential to promote the patient.