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小儿法洛氏四联症体外循环术后出血的临床观察

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目的:观察小儿法洛氏四联症体外循环术后血小板计数的变化及出血量,及早干预术后出血,减少异常出血的发生。方法随机选择47例确诊为先天性心脏病择期进行心内直视手术的患儿,27例法洛氏四联症的患儿( TOF组)作为本次研究对象,20例室间隔缺损患儿( VSD组)作为对照组。记录两组体外循环转流时间、体外循环温度,记录两组患儿术前、术后即刻、24小时、48小时及72小时的血小板计数,同时观察并记录术后24小时胸腔积液引流量的情况。结果术后即刻至术后48小时TOF组患儿血小板计数较VSD组患儿低,差异显著,有统计学意义(P<0.05)。 TOF组患儿术后72小时血小板计数恢复接近正常水平,VSD组患儿术后24h恢复至正常水平(>100×109/L)。体外循环术中 TOF组患儿体外循环转流时间长于 VSD 组患儿,且TOF患儿肛温低于VSD组患儿(P<0.05)。 TOF组患儿术后24小时出血量明显高于VSD组患儿(P<0.05)。结论 TOF患儿体外循环术后的血小板计数下降明显体外循环时间、温度是影响血小板计数减少的高危因素,并增加患儿术后血性胸腔引流量。 TOF患儿体外循环术后早期需要更多的止血干预。
Clinical Observation of Hemorrhage in Children with Tetralogy of Fallot after Cardiopulmonary bypass
Objective Observe the change of platelet count and the amount of bleeding to children with tetralogy of Fallot after cardiopulmonary bypass early inter-vention of postoperative bleeding,reduce the abnormal bleeding.Methods Random selection 27 cases of the children with tetra logy of Fallot as the research object(TOF group) ,20 cases of the children with ventricular septal defect as the control group ( VSD group) .Cardiopulmonary bypass time and cardiopulmonary bypass temperature were recorded.All patients were collected blood samples for routine blood test.Platelet count(PLT)were recorded at the 0th,24th,48th and 72th hours post-operation. The blood loss of the pleural effusion drainage was recorded for patients at the 24th hour post-operation.Results Platelet count values of TOF group are lower than that of VSD group from right now post operation to 48 hours post operation,significant difference,there was statistically significant(P<0.05).Platelet count values of TOF group return to the normal range after 72 hours in post CPB and the values of VSD group return after 24 hours( >100 ×109/L).The CPB time values of TOF group are significantly longer than that of VSD group(P<0.05),and the CPB temperature values of TOF group are significantly lower than that of VSD group(P<0.05).The pleural effusion drainage bleeding values of TOF group are significantly higher than that of VSD group(P<0.05).Conclusion Platelet count values of TOF group are de-creased significantly.Platelet count values of TOF group are higher than that of VSD group.The time and temperature of cardiopulmonary bypass are the higher risk rea-sons.Cardiopulmonary bypass lead pleural drainage bleeding values of TOF group to increase.Children with TOF need more hemostasis intervention after cardiopulmonary bypass early.

ChildrenTetralogy of FallotCardiopulmonary bypassBleeding

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山东省临沂市妇幼保健院心脏中心,山东 临沂 276000

小儿 法洛氏四联症 体外循环 出血

2014

中国保健营养(上旬刊)
全国卫生产业企业管理协会

中国保健营养(上旬刊)

ISSN:1004-7484
年,卷(期):2014.(4)
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