Objective To explore the psychological care of patients with breast cancer .Method 45 patients with breast cancer patients get for operation .Postopera-tive by talking with the patient,understand the absence of breast concerns,according to the psychological change,with the key,for psychological therapy and correspond-ing nursing.Results 45 patients could happily accepted radiotherapy and chemotherapy,mental state intact,self image recognition,social ability improved,improved qual-ity of life.Patients were followed up for 6-12 months,no local recurrence,1 cases of liver metastasis.Conclusion Correct,targeted psychological care,is not only closely to understand the relationship between nurses and patients,but also increase the confidence of the patients,improve the quality of life of the treatment effect and patient.