Clinical analysis on 74 patients with poststroke seizures and epilepsy
Objective To study the clinical features of poststroke seizures and epilepsy .Methods Medical documents of 74 patients with poststroke seizures and epi-lepsy,accounting for 7.6% of 972 consecutive stroke patients from 2003 July to 2008 June,were retrospectively analyzed.Results Seizures were developed in 47 patients with ischemic stroke(6.8%),and in 24 patients with intracerebral hemorrhage(8.8%),and in 3 patients with subarachnoid hemorrhage(30.0%).There were 58 pa-tients with early seizures and 16 patients with late seizures,respectively.Among 47 patients with seizures after ischemic stroke,24 patients suffered from cortical infarct, 14 from subcortical infarct,and 9 from massive infarct.Among 24 patients with seizures after intracerebral hemorrhage ,16 patients suffered from cortical hemorrhage and 8 from subcortical hemorrhage.Routine electroencephalography was performed in 42 patients with seizures,epileptiform discharge was seen in 14 patients,paroxysmal dif-fused slow activity in 4 and the rest 24 patients did not show apparent abnormality.Four patients with early seizures died within 7 days.Ten and 3 patients with poststroke epilepsy got free from seizures after 1 and 2 years of medical treatment,respectively;4 patients keep on medical treatment for an average time of 2.5 years;4 died and 2 lost during follow-up.Conclusion Cortical lesions,massive infarcts and hemorrhagic stroke may be predictors for poststroke seizures .Late poststroke seizure may be a risk factor for poststroke epilepsy.The diagnosis of poststroke seizures was mainly based on an accurate description of manifestation and some new anti -epileptic drugs can be the first-line monotherapy in patients with poststroke seizures and epilepsy .
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