幽门螺杆菌阳性的原发性胆汁反流性胃炎45例治疗分析
TREAT ANALYSIS OF HELICOBACTER PYLORI-POSITIVE PATIENTS WITH PRIMARY BILE REFLUX GASTRITIS
王学敏 1石荣亚2
作者信息
- 1. 河北省保定市第三医院,河北 保定 071000
- 2. 保定传染病医院,河北 保定 071000
- 折叠
摘要
目的:探讨幽门螺杆菌(HP)阳性的原发性胆汁反流性胃炎的临床治疗方法。方法将90例HP阳性原发性胆汁反流性胃炎患者随机分为试验组和对照组各45例,试验组予以莫沙必利+奥美拉唑+左氧氟沙星+阿莫西林四联疗法,对照组予以莫沙必利+奥美拉唑两联治疗,观察并比较2组的临床疗效及HP根除率。结果试验组临床有效率为85%,HP根除率为82%,远远高于对照组的63%、10%,有统计学意义(P<0.05)。结论对于合并HP感染的原发性胆汁反流性胃炎,左氧氟沙星+阿莫西林+莫沙必利+奥美拉唑四联疗法能取得满意的临床疗效及提高HP根除率。
Abstract
Objective To investigate the clinical treatment options of helicobacter pylori -positive patients with primary bile reflux gastritis .Methods 90 helicobact-er pylori-positive patients with primary bile reflux gastritis were randomized to the test group or the control group in 1:1 ratio,45 patients per group.The patients in the control group received mosapride plus omeprazole,and the patients in the test group,besides the two drugs described above,also received levofloxacin and amoxicillin. Observe and compare the efficacy and eradication rate between two groups.Results The overall clinical effective rate and eradication rate in the test group (85% and 82%,respectively)were statistically significantly higher than that of the control group(63% and 10%,respectively;P<0.05).Conclusion The helicobacter pylori erad-ication therapy is better for the helicobacter pylori -positive patients with primary bile reflux gastritis .
关键词
胆汁反流性胃炎/幽门螺杆菌/左氧氟沙星+阿莫西林+莫沙必利+奥美拉唑四联疗法Key words
Bile Reflux Gastritis/Helicobacter Pylori引用本文复制引用
出版年
2014