哮喘患者并幽门螺杆菌感染的临床分析
Clinical analysis of asthmatics with Helicobacter pylori infection
任庆伟1
作者信息
- 1. 山东东营胜利油田胜利医院，山东东营 257055
- 折叠
摘要
目的：探讨哮喘患者中幽门螺杆菌（Hebcobacter pylori，Hp）的感染情况及其临床意义。方法将180例哮喘患者分为儿童组和成人组，计算各组HP感染率，分别与对照组比较，并做组间比较。并将哮喘患者根据有无Hp感染分组，测定肺功能并进行比较。用13C呼气试验（13C -UBT）法检测病人幽门螺杆菌感染情况。结果180例哮喘病人中，56名患者Hp感染，阳性率为31．11％；110例对照组中48人 Hp 感染，阳性率为43．64％（p＝0．031）。其中儿童哮喘患者Hp感染率较其正常对照明显降低，而成人哮喘患者 Hp 感染率与正常对照无明显差异。哮喘患者合并 Hp感染后其肺功能明显下降。结论幽门螺杆菌感染与哮喘呈负相关，在儿童组较明显。哮喘合并Hp感染后会加重肺损伤。
Abstract
Objective To investigate the role of Helicobacter pylori(Hp)infection in asthmatics.Methods We divided 180 asthmatics into two groups(children and adults)according to the age.Hp infection was detected using 13C-UBT.The infection rate between each group was mesured by t -test using SPSS 17.0.Result The in-fetion rate of Hp was significantly lower in asthmatics than controls(p=0.031),espeially among children.Asthamatics with Helicobacter pylori infection had worse lung fuction than those without Hp infection.Conclusion Helicobacter pylori infection was negatively related to asthma,especially in children group.
关键词
哮喘/幽门螺杆菌/肺功能Key words
Asthma/Helicobacter pylori/Lung function引用本文复制引用
出版年
2014
NETL
NSTL
万方数据