Objective to analyze the application of the rehabilitation nursing pathway in patients with colon cancer surgery effect .Methods The research object to choose self court in March 2011-of colon cancer patients admitted in March 2012,a total of 36 cases,control group patients with routine nursing,the experimental group patients rehabilitation nursing path,compared two groups of patients in hospital time,cost,and postoperative self-care ability and health knowledge.Results Two groups of patients were recovered and discharged,shorter hospitalization time than the control group ,experimental group patients hospitalized costs should be lower than the con-trol group,degree of health knowledge mastering and postoperative self -care ability score significantly higher than that of control group,there are significant differences, p <0.05,with statistical significance.Conclusion Application of nursing patients with colon cancer surgery recovery path can improve the effect of nursing ,prompting pa-tients resumed as soon as possible.