Objective To explore the value of The Application Value of 1H-magnetic resonance spectroscopy in children multiple sclerosis.Methods Both 24 pa-tients with MS and 20 healthy volunteers underwent lH-MRS.The Nacetylas Partic acid(NAA),choline(Cho),creatine(Cr),Lipid(Lip),lactic acid(Lac)and my-oinositol(mI)peaks were measured in each region of interest,and NAWM were analyzed.Results NAA/Cr、Cho/Cr and NAA/Cho were significantly different among the Acute plaques,Chronic plaques and the NAWM(P<0.05).Conclusion 1H-MRS provide important information research to children of MS,and can be used for moni-toring and evaluation of the progression of prognosis.
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