A Study of the Association between Fasting Blood Glucose Levels and Risk of Death in Patients with Ischemic Stroke
OBJECTIVE To evaluate the association between fasting blood glucose levels and risk of death in ischemic stroke patients in Songjiang,Shanghai,to provide a scientific basis for improving the prognosis of patients.METHODS A prospective cohort study was conducted on 1 368 patients with ischemic stroke in the community from April 2016 to September 2017,and the data of patients'age,gender,disease history,biochemical indexes and other data were collected,and univariate and multivariate COX regression analysis was used to evaluate the relationship between different FBP levels and the death of IS patients.RESULTS During a median follow-up period of 6.24 years and a total follow-up period of 8 454.16 person-years for 1 368 ischemic stroke patients,there were a total of 114 deaths,with a density of deaths of 13.48/1 000 person-years,and a cumulative mortality rate of 8.33%.Restricted triple spline analyses were performed to show that that there was a dose-response relationship between FBP levels and the risk of death in ischemic stroke patients;multifactorial COX regression model analysis showed that FBP level≥7.0 mmol/L was associated with an increased risk of death in patients with ischemic stroke,and the association persisted after stratification by gender,smoking,alcohol consumption,hypertension,overweight obesity,and dyslipidemia.CONCLUSION FBP≥7.0 mmol/L in community ischemic stroke patients are independently associated with patient death,and it is recommended to pay attention to and control patients'glucose levels to better improve their prognosis.
ischemic strokefasting blood glucosecommunitycohort studyrisk of death
万方数据
维普
