Double perovskite compounds have attracted wide attention due to the advantages of low phonon energy,easy doping with rare earth ions,and stable physicochemical properties. To obtain novel temperature-sensitive up-conversion ma-terials,a series of up-conversion luminescent materials K3InF6:Er3+,Yb3+with double perovskite structure were synthesized by high-temperature solid-phase method in this paper. In addition,the composition,structure and luminescence properties were systematically characterized by X-ray powder diffractometer (XRD),field emission scanning electron microscope (FE-SEM) and fluorescence spectrometer (PL),respectively. The results show that the prepared up-conversion luminescent ma-terials are all double perovskite structure,and the samples emit bright green light under 980 nm laser excitation,and the up-conversion luminescence intensity of the samples is maximized when the ratio of amounts of Er3+and Yb3+are 0.05 and 0.25,respectively. Meanwhile,the up-conversion luminescence mechanism involved in the samples is discussed in detail by measuring the up-conversion luminescence spectra of variable power. The temperature sensing performance of the samples in the range of 303 to 573 K was also investigated based on the fluorescence intensity ratio ( FIR) technique,and a maximum absolute sensitivity of 9.5×10-3 K-1 was obtained when the temperature was 483 K. All the results indicate that K3InF6:Er3+,Yb3+up-conversion luminescent material has high sensitivity and has a promising application in the field of temperature sensing.