评估射频消融对不同大小甲状腺良恶性结节的短期疗效
Evaluation of the Short-Term Efficacy of RFA in Different Size of Benign and Malignant Thyroid Nodules
崔文芳 1马家莉 1梁汝娜 1王娟 1曹茹 1何鑫 1姜珏1
作者信息
- 1. 西安交通大学第二附属医院超声科 西安市,710004
- 折叠
摘要
目的 评估超声引导下射频消融治疗对不同大小甲状腺良恶性结节的有效性和安全性.方法 前瞻性收集接受射频消融的157例患者共252个结节,评估射频消融治疗后第1、第3、第6、第9个月时甲状腺结节横径、纵径的大小变化,直径缩小率和治愈率及治疗后出现的并发症.结果 157例患者共252个甲状腺结节的横径、纵径在消融术后第1、第3、第6、第9个月逐渐减小,缩小率递增且其直径变化差异具有统计学意义;甲状腺微小乳头状癌第6个月时消失最多,≤5 mm甲状腺微小乳头状癌9个月时累积治愈率最高;甲状腺良性结节方面,≤15 mm良性结节第9个月累积治愈率为81.6％,而＞15 mm良性结节第9个月难以通过射频消融达到完全治愈;≤10 mm甲状腺良性结节与≤10 mm甲状腺微小乳头状癌横径、纵径变化及结节累积治愈率差异均无统计学意义.结论 超声引导下射频消融能够有效治疗甲状腺良恶性结节,尤其适用于≤5 mm甲状腺微小乳头状癌,治愈率最高.
Abstract
Objective To evaluate the efficacy and safety of ultrasound-guided radiofrequency ablation(RFA)in the treatment of different size benign and malignant thyroid nodules.Methods A total of 252 nodules in 157 patients who underwent radiofrequency ablation were selected.The size change in transverse and longitudinal diameter,diame-ter reduction rate and the cure rate of thyroid nodules at 1,3,6 and 9 months after radiofrequency ablation,and the complication occurrence after treatment were evaluated.Results The transverse and longitudinal diameter of 252 thy-roid nodules were gradually decreased at the 1,3,6 and 9 months after ablation,the reduction rate was increased,and there were statistically significant differences in diameter changes.Papillary thyroid microcarcinoma disappeared most-ly at 6 months,the highest cumulative cure rate of papillary thyroid microcarcinoma less and equal than 5mm was at 9 month.In term of benign thyroid nodules,the cumulative cure rate was 81.6％in nodules less and equal than 15 mm,and it were difficult to achieve complete cure by radiofrequency ablation in nodules more than 15 mm.There were no statistically significant differences in transverse and longitudinal diameter change and cumulative cure rate between be-nign nodules and papillary thyroid microcarcinoma less and equal than 10 mm.Conclusions Ultrasound-guided radio-frequency ablation can treat thyroid nodules effectively,especially with the highest cure rate in 5 mm papillary thyroid microcarcinoma.
关键词
甲状腺结节/超声引导下射频消融/甲状腺微小乳头状癌/甲状腺良性结节Key words
Thyroid nodule/Ultrasound-guided radiofrequency ablation/Papillary thyroid microcarcinoma/Be-nign thyroid nodule引用本文复制引用
出版年
2025
NETL
NSTL
万方数据