Study on the efficacy of magnesium sulfate and ritodrine hydrochloride in the treatment of placenta previa
Objective To explore the clinical efficacy and safety of magnesium sulfate and ritodrine hydrochloride in the treatment of placenta previa,and to provide a basis for the clinical treatment of placenta previa.Methods A total of 78 patients with placenta previa admitted to Gaotang County People's Hospital from November 2018 to November 2020 were selected and divided into an observation group and a control group according to the random number table method,with 39 cases in each group.The control group was treated with magnesium sulfate,while the observation group was treated with ritodrine hydrochloride.The time of gestational week extension,postpartum bleeding volume,neonatal Apgar score,neonatal body weight,full-term pregnancy rate,success rate of fetal preservation,vaginal delivery rate and incidence of adverse reactions between two groups were compared.Results The time of gestational week extension in the observation group was longer than that in the control group,postpartum bleeding volume was less than that in the control group,the Apgar score and body weight of newborns in the observation group were better than those in the control group,and the differences were statistically significant(P＜0.05).The full-term pregnancy rate,success rate of fetal preservation and vaginal delivery rate in the observation group were 92.31％,94.87％and 92.31％,which were all higher than those in the control group with 69.23％,76.92％and 71.79％,and the differences were statistically significant(P＜0.05).The incidence of adverse reactions in the observation group was 5.13％,while the incidence of adverse reactions in the control group was 10.26％,and the difference was not statistically significant between the two groups(x2=0.180 6,P＞0.05).Conclusion The application of ritodrine hydrochloride in the treatment of placenta previa had good therapeutic effects,could effectively prolong gestational week,reduce postpartum bleeding volume,improve the success rate of fetal preservation and vaginal delivery rate,and had certain safety,which was worthy of clinical application and promotion.
万方数据
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