Clinical study on interventional therapy for acute cerebral infarction within 4.5 h after onset
Objective To analyze the clinical effect of interventional treatment for acute cerebral infarction within 4.5 h after onset,in order to provide reference for the formulation of clinical treatment plans.Methods A total of sixty patients with suspected large vessel stenosis with a national institute of health stroke scale(NIHSS)score greater than 6 points admitted to Liaocheng Chiping District People's Hospital from January 2020 to December 2022 were selected as the observation subjects.They were randomly divided into control group and study group,with 30 cases in each group.The control group received medication thrombolysis treatment,while the study group received intravenous thrombolysis bridging intervention treatment.The treatment effect,neuron specific enolase(NSE)and homocysteine(Hey)levels between two groups were compared.Results The total effective rate of treatment in the study group was 73.33％,which was higher than that in the control group with 33.33％,and the difference was statistically significant(x2=9.643,P＜0.05).Before treatment,the NSE and Hcy levels in the study group were(27.51± 3.92)μg/L and(22.25±1.54)μmol/L,while those in the control group were(27.34±3.26)μg/L and(22.24±1.55)µmol/L,and the differences were not statistically significant(t=0.183,0.025,allP＞0.05);after treatment,the NSE and Hcy levels in the study group were(14.54±2.14)μg/L and(11.46±2.25)µmol/L,which were lower than those in the control group with(17.12±2.81)μg/L and(15.72±1.49)µmol/L,and the differences were statistically significant(t=4.001,8.646,all P＜0.05).Conclusion In the clinical treatment of patients with acute cerebral infarction within 4.5 h after onset,interventional therapy could effectively reduce NSE and Hcy levels,improve neurological function and mental state,reduce brain tissue damage,and had higher clinical application value.
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