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左氨氯地平联合卡托普利治疗高血压的效果

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目的 采用组间对比的形式,在观察左氨氯地平联合卡托普利治疗高血压的效果的基础上,对该疗法的安全性和有效性进行重点分析.方法 选取2021年1月—2023年1月天津市河东区东新街社区卫生服务中心收治的30例高血压患者为研究对象,将30例患者的性别、年龄等基础信息录入到Excel软件中进行随机分组.本次对照研究共设置两组,其中一组由15例接受左氨氯地平治疗的患者为对照组;另外一组由15例接受左氨氯地平联合卡托普利治疗的患者为观察组.根据多种观察指标评估两组血压水平、治疗有效率及不良反应发生率.结果 从抗高血压作用来看,治疗后观察组与对照组的舒张压(DBP)分别为(83.34±5.28)、(88.19±5.23)mmHg,收缩压(SBP)分别为(128.46±10.23)、(137.36±12.18)mmHg,观察组较对照组均更低,差异有统计学意义(P<0.05).从治疗有效性方面来看,观察组治疗总有效率为100.00%,高于对照组的73.33%,差异有统计学意义(χ2=4.615 4,P<0.05).从治疗安全性方面来看,观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05).结论 左氨氯地平联合卡托普利治疗高血压的效果良好,相较于单纯使用左氨氯地平,该疗法的应用能发挥出更强的抗高血压作用,兼具安全性和有效性,值得临床推广.
Effect of levamlodipine combined with captopril in the treatment of hypertension
Objective Based on the observation of the effect of levamlodipine combined with captopril in the treatment of hypertension in the form of inter-group comparison,the safety and effectiveness of the treatment were emphatically analyzed.Methods A total of 30 hypertensive patients admitted to Tianjin Hedong District Dongxin Street Community Health Service Center from January 2021 to January 2023 were selected as the research subjects.Basic information such as gender and age of the 30 patients were entered into Excel software for random grouping.This controlled trial consisted of two groups,one of which consisted of 15 patients who received treatment with levamlodipine and was named the control group;the other group consisted of 15 patients who received treatment with levamlodipine combined with captopril,and was named the observation group.The blood pressure levels,treatment effectiveness,and the incidence of adverse reactions of two groups based on multiple observation indicators were evaluated.Results From the perspective of antihypertensive effects,the diastolic blood pressure(DBP)of the observation group and the control group after treatment were(83.34±5.28)and(88.19±5.23)mmHg,and the systolic blood pressure(SBP)were(128.46±10.23)and(137.36±12.18)mmHg,respectively,and the observation group were lower than the control group,and the differences were statistically significant(P<0.05).In terms of treatment effectiveness,the total effective rate of treatment in the observation group was 100.00%,which was higher than 73.33%in the control group,and the difference was statistically significant(χ2=4.615 4,P<0.05).From the perspective of treatment safety,the incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The combination of levamlodipine and captopril had a good effect on the treatment of hypertension.Compared to using levamlodipine alone,the application of this therapy could exert stronger anti hypertensive effects,with both safety and effectiveness,and which was worthy of clinical promotion.

HypertensionLevamlodipineCaptoprilTreatment effect

刘霜

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天津市河东区东新街社区卫生服务中心西药房,天津 300162

高血压 左氨氯地平 卡托普利 治疗效果

2024

中国城乡企业卫生
中华预防医学会 天津市职业病防治院

中国城乡企业卫生

影响因子:0.239
ISSN:1003-5052
年,卷(期):2024.39(2)
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