Study of cytomegalovirus detection results in infant blood,urine and breast milk
Objective To analyze the results of cytomegalovirus DNA testing in infant blood,urine and maternal breast milk,in order to improve the clinical detection rate of cytomegalovirus.Methods From August 2022 to August 2023,the blood,urine and maternal breast milk of 55 infants suspected of being infected with cytomegalovirus who received breastfeeding at Liaocheng City Dongchangfu District Maternal and Child Health Hospital were tested for cytomegalovirus DNA.The detection was performed using fully automated fluorescence quantitative PCR method.The detection rates of cytomegalovirus in infant blood,urine and breast milk samples were compared,and the detection rates of cytomegalovirus in breast milk samples and the combination of the three were compared.Results The detection rate of cytomegalovirus DNA in blood samples was 27.27％,the detection rate in urine samples was 41.82％,and the detection rate in breast milk samples was 43.64％,breast milk had the highest detection rate,and there were no statistically significant differences in detection rates among the three samples(P＞0.05).The combined detection rate of the three was 63.64％,which was higher than 43.64％of breast milk samples,and the difference was statistically significant(x2=4.423,P＜0.05).Conclusion The detection of cytomegalovirus DNA in infant blood,urine and breast milk was beneficial for disease diagnosis.If the sample of the child was not easily obtainable,priority should be given to selecting breast milk or urine with high detection rates.Blood,urine and breast milk could also be tested simultaneously to improve the detection rate of cytomegalovirus,thereby achieving the goal of early diagnosis and treatment,and promoting the child's early recovery.
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