Analysis of bacterial drug resistance monitoring in clinical microbiological testing
Objective To observe the application effect of bacterial drug resistance monitoring in clinical microbiological testing,to explore the application value of bacterial drug resistance monitoring,in order to promote the improvement of clinical medication safety and standardization.Methods The bacterial drug resistance of 300 pathogenic bacteria isolated from the testing samples collected by Fujian Province Ninghua County General Hospital from January 1,2021 to January 1,2023 was monitored,and the distribution of bacterial strains was understood through clinical microbiological testing,and the bacterial drug resistance monitoring results were analyzed.Results Among the 300 case of pathogenic bacteria,the detection rate of Escherichia coli was the highest,accounting for 16.00％,followed by Pseudomonas aeruginosa,accounting for 14.33％,Klebsiella pneumoniae,accounting for 12.67％,and the lowest was Streptococcus pneumoniae,accounting for 1.00％.Analysis of bacterial drug resistance monitoring results:Escherichia coli,Pseudomonas aeruginosa and Klebsiella pneumoniae,which accounted for the top three,had the highest drug resistance to cefuroxime,with 79.17％,100.00％and 52.63％,respectively,among them Escherichia coli had the lowest drug resistance to meropenem,accounting for 6.25％,and Pseudomonas aeruginosa had the lowest drug resistance to amikacin,accounting for 11.63％,Klebsiella pneumoniae had the lowest drug resistance to imipenem,accounting for 0.00％.Compared with the other two pathogenic bacteria,Pseudomonas aeruginosa had the highest drug resistance to cefuroxime and amtreonam,and the differences were statistically significant(P＜0.05);compared with the other two pathogenic bacteria,Escherichia coli had the highest drug resistance to ciprofloxacin,and the differences were statistically significant(P＜0.05).Conclusion The application effect of bacterial drug resistance monitoring in clinical microbiological testing was good,which could improve the detection rate of bacteria and comprehensively obtaining the change of drug resistance,which was conducive to the selection of appropriate treatment drugs for patients by clinical medical staff,and it was worthy of clinical promotion and application.
Microbiological testingBacterial drug resistanceClinical effect
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