Treatment analysis of hypothyroidism after hyperthyroidism treatment
Objective To analyze the incidence of complications of hypothyroidism after hyperthyroidism treatment and summarize preventive measures to guide subsequent clinical work.Methods A total of 102 patients with hyperthyroidism admitted to Tengzhou Central People's Hospital from January 2021 to January 2022 were selected.They were divided into study group and control group based on the treatment method,with 51 patients in each group.The study group received treatment with methimazole,while the control group received 131I radiation therapy.The occurrence of hypothyroidism between two groups were compared.Results After treatment,there was 1 case of hypothyroidism and 1 case of subclinical hypothyroidism in the study group,totaling 2 cases.There were 8 cases of hypothyroidism and 2 cases of subclinical hypothyroidism in the control group,totaling 10 cases.The incidence rate of hypothyroidism in the study group was 3.92％,which was lower than 19.61％in the control group,and the difference was statistically significant(x2=6.044,P＜0.05).Among the 12 patients with hypothyroidism,7 cases had FT3 below normal,9 cases had FT4 below normal,and 10 cases had TSH above normal.Conclusion For patients with hyperthyroidism treated with 131I radiation therapy,timely monitoring of the patient's various indications and follow-up work were necessary in clinical practice.Compared to 131I radiation therapy,early use of methimazole therapy could effectively reduce the incidence of hypothyroidism,which had higher clinical application value.
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