Clinical rational application of cephalosporin antibiotics
Objective To explore the clinical rational application of cephalosporin antibiotics,in order to provide reference for antibiotic use and management.Methods A retrospective survey was conducted on the use of cephalosporin antibiotics in Xing'an Central Health Center of Gaocheng District from January 2021 to December 2022,and the medication situation was statistically analyzed.Results Between January 2021 and December 2022,a total of 8 cephalosporins were studied,including 4 types for oral administration and 4 types for injection;according to the number of varieties,the most common was the third-generation cephalosporin,with a total of 5 types;the first generation was one type,among which the third-generation cephalosporin antibiotics had the highest frequency of use(DDDs)and cost of use,followed by the second generation.By analyzing the types of cephalosporin antibiotics used,drug utilization index(DUI)and DDDs,it was found that among the four drugs of cefradine,ceftriaxone,cefdinib and cefixime,ceftriaxone had the highest amount of medication,as well as the highest DUI and DDDs,indicating the most reasonable use of medication.Conclusion The daily use of cephalosporin antibiotics was relatively reasonable,and most of them were accompanied by a relatively high starting point of use.Therefore,during the clinical use of cephalosporin antibiotics,the management of cephalosporin antibiotics should be strengthened to ensure reasonable drug use,reduce the incidence of unreasonable drug use,and ensure the safety of patient treatment.
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