The study on the effect of acitretin combined with Xiaoyin Tablets in the treatment of head psoriasis
Objective To study clinical efficacy of acitretin combined with Xiaoyin Tablets in the treatment of head psoriasis patients and its impact on the severity of disease condition,quality of life and other factors of patients.Methods A total of 98 cases of head psoriasis admitted to Liaocheng Chiping District People's Hospital from June 2022 to October 2023 were selected and divided into control group and observation group according to different treatment plans,with 49 cases in each group.The control group was treated with acitretin,the observation group was treated with acitretin combined with Xiaoyin Tablets.The clinical efficacy,the skin lesion severity score,the incidence of adverse reaction and the score of life quality of patients between two groups were compared.Results The total effective rate of the observation group was 93.88％,which was higher than that of the control group with 77.55％,and the difference was statistically significant(x2=5.333,P＜0.05).Before treatment,there was no statistically significant difference in PASI scores between the two groups(P＞0.05);after 4 and 8 weeks of treatment,the PASI scores of the two groups were lower than before treatment,and the observation group was significantly lower than the control group,and the differences were statistically significant(P＜0.05).Before treatment,there were no statistically significant differences in health status and physiological function scores between the two groups(P＞0.05);after treatment,the health status and physiological function scores of the two groups were higher than before treatment,and the scores of observation group were higher than those of the control group,and the differences were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The clinical efficacy of acitretin cmobined with Xiaoyin Tablets in the treatment of head psoriasis patients was definite,which could effectively improve the patient's condition and symptoms,enhance their quality of life and have high drug safety,which was worthy of clinical promotion and application.
AcitretinXiaoyin TabletsPsoriasis of the headClinical efficacyAdverse reactions
万方数据
维普
