Research progress of T-cadherin in coronary heart disease
T-cadherin(T-cad)is a newly discovered adiponectin receptor,which can bind to adiponectin hexamer and high molecular weight polymer.T-cad is widely expressed in many tissues in vivo,especially in the cardiovascular system.T-cad is closely related to coronary heart disease,and has the effects of inhibiting cell apoptosis,preventing ath-erosclerosis,limiting vascular intimal hyperplasia,inducing vascular endothelial cell proliferation,promoting the secretion of growth factors,and promoting muscle regeneration.Therefore,exploring the mechanism of T-cad in coronary heart dis-ease may provide new ideas for the diagnosis and treatment of coronary heart disease.
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