首页|三维超声心动图右心室特征对急性左心室下壁心肌梗死患者PCI术后心力衰竭的预测价值

三维超声心动图右心室特征对急性左心室下壁心肌梗死患者PCI术后心力衰竭的预测价值

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[目的]探究三维超声心动图右心室特征对急性左心室下壁心肌梗死(INFMI)患者经皮冠状动脉介入治疗(PCI)后心力衰竭(HF)的预测价值.[方法]纳入2018年10月-2021年10月261例INFMI患者,根据PCI术后1年随访记录分为心力衰竭组(n=42)和无心力衰竭组(n=219).比较两组临床资料和心动图特征;采用LASSO-Logistic回归筛选术后HF发生的独立影响因素;构建列线图模型并验证.[结果]经筛选,在最优λ 值处LASSO模型纳入INFMI患者游离壁中间段和整体纵向应变、流入道舒张期末容积和射血分数、体部舒张期末容积和射血分数.术后体部射血分数降低(截断值43.27%)、流入道射血分数降低(截断值51.49%)、整体纵向应变升高(截断值-13.52%)对HF有较高预测价值.联合年龄、Killip分级、N末端脑钠肽前体(NT-proBNP)构建列线图模型区分度较高,一致性指数0.981(95%CI:0.872~0.997),预测值与实际值拟合度较好.[结论]INFMI患者右心室整体纵向应变、流入道和体部射血分数联合年龄、Killip分级、NT-proBNP对PCI术后1年HF风险具有较高的预测价值,预测模型可作为临床决策工具使用.
Predictive value of right ventricular features on three-dimensional echocardiography for heart failure after PCI in patients with inferior wall myocardial infarction
Aim To investigate the predictive value of right ventricular features on three-dimensional echocardio-graphy for heart failure(HF)after percutaneous coronary intervention(PCI)in patients with inferior wall myocardial in-farction(INFMI).Methods 261 patients with INFMI from October 2018 to October 2021 were included.Patients were divided into heart failure group(n=42)and no heart failure group(n=219)based on one-year follow-up records af-ter PCI.Clinical data and echocardiographic characteristics of the two groups were compared.LASSO-Logistic regression was used to screen the independent influencing factors for the occurrence of postoperative HF.A column-line diagram model was constructed and validated.Results After screening,the LASSO model at the optimal λ value in-corporated free wall mid-segment and global longitudinal strain,inflow tract end-diastolic volume and ejection fraction,and body end-diastolic volume and ejection fraction in INFMI patients.Higher predictive value for HF was found in lower postoperative body ejection fraction(cutoff value 43.27%),lower inflow tract ejection fraction(cutoff value 51.49%),and higher global longitudinal strain(cutoff value-13.52%).Ultrasound indices combined with age,Killip classification,and N-terminal pro-brain natriuretic peptide(NT-proBNP)were used to construct a columnar graphical model.The model was highly discriminative,with a consistency index of 0.981(95%CI:0.872~0.997).The model predicted values fitted well with the actual values.Conclusion Right ventricular global longitudinal strain,inflow tract ejection fraction,body ejection fraction,age,Killip classification,and NT-proBNP in patients with INFMI have a high predictive value for the risk of HF one year after PCI.The jointly constructed prediction model can be used as a clinical decision-making tool.

acute myocardial infarctionechocardiographypercutaneous coronary interventionheart failure

郭园园、王雲雲、李海龙

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潍坊市中医院急诊科,山东省潍坊市 216000

急性心肌梗死 超声心动图 经皮冠状动脉介入治疗 心力衰竭

2024

中国动脉硬化杂志
中国病理生理学会 南华大学

中国动脉硬化杂志

CSTPCD
影响因子:1.086
ISSN:1007-3949
年,卷(期):2024.32(2)
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