Regulation of lymphangiogenesis in the arterial wall by macrophages
Macrophages play multiple roles in atherosclerosis.The progression of atherosclerosis is associated with morphological and functional changes in the lymphatic vessels of the diseased arteries,but the mechanism is not fully un-derstood.This paper mainly reviews the origin and classification,the markers and the function of macrophage in athero-sclerosis,the origin,the structure function and the markers of lymphatic vessels in atherosclerosis,the changes of arterial wall lymphangiogenesis in different stages of atherosclerotic lesions,the functional role of lymphangiogenesis in atheroscle-rosis,the lymphatic migration of macrophages and its mechanism involved in lymphangiogenesis,in order to provide a basis for the mechanism research and clinical treatment of atherosclerosis.
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