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Non-invasive Observation of Human Tissue Samples with Full Field Optical Coherence Tomography

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In this work,we report on non-invasive observation of human esophagus,liver,and uterus samples with Full field optical coherence tomography (FFOCT).ln imaging process,fresh human samples were fixed in formalin immediately after excision and then imaged directly without staining and cutting the samples into a serial of thin slices.Tissue microstructures of each type of normal or cancerous tissue as well as their changes with the increase of the depth beneath tissue surface can be identified in the depth-resolved images.The results demonstrate the potential of applications of the en face images in clinic practice.

En face imagesOptical sectioning imagingFull field optical coherence tomography (FFOCT)Tissue microstructures

MU Ning、GAO Wanrong、ZHOU Yawen

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Department of Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China

This work is supported by the National Natural Science Foundation of ChinaThis work is supported by the National Natural Science Foundation of ChinaKey Special Projects of "Major Scientific Instruments and Equipment Development" of the National Key Research and Developmen

61275198609780692017YFF0107100

2019

10.1049/cje.2019.06.018

中国电子杂志(英文版)

中国电子杂志(英文版)

CSTPCDCSCDSCIEI
ISSN：1022-4653
年,卷(期)：2019.28(5)
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