Allergic rhinitis(AR)is a type Ⅰ allergic reaction mainly mediated by immunoglobulin E(IgE),which is involved in various immune cells and cytokines.At present,the prevalence of AR is increasing year by year.There are many problems in clinical treatment,and its pathogenesis needs further study.Recently,the in-depth study of intestinal microbiota found that intestinal microbiota and its metabolites could interact with multiple organs through neural,immune and endocrine pathways.For example,the regulation of the immune system affected asthma,AR and other allergic diseases.Therefore,intestinal microbiota disorders may be one of the mechanisms of the pathogenesis of AR.In this paper,we reviewed intestinal microbiota,the impact of intestinal microbiota on immune system,the relationship between intestinal microbiota and AR,as well as the application of probiotics,prebiotics and bacterial lysates.It will provide a new reference for the treatment of AR.
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